GPX4 anticorps (Glutathione Peroxidase) (Alexa Fluor 647)

Details for Product anti-GPX4 Antibody No. ABIN899662, Fournisseur: Connectez-vous pour afficher
Antigène
  • GPx-4
  • GSHPx-4
  • MCSP
  • PHGPx
  • snGPx
  • snPHGPx
  • Phgpx
  • gpx-4
  • snGpx
  • cb563
  • cb691
  • PHGPxa
  • sb:cb563
  • zgc:92253
  • wu:fb82e03
  • 1700027O09Rik
  • mtPHGPx
  • ATGPX4
  • F11L15.5
  • glutathione peroxidase 4
  • GP-GPx4
  • glutathione peroxidase 4
  • glutathione peroxidase 4a
  • GPX4
  • Gpx4
  • gpx4a
Reactivité
Humain, Souris, Rat (Rattus)
93
50
42
4
3
3
2
2
1
1
Hôte
Lapin
64
19
19
Clonalité
Polyclonal
Conjugué
Cet anticorp GPX4 est conjugé à/à la Alexa Fluor 647
5
5
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
71
46
37
21
15
12
8
5
4
3
1
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human Glutathione Peroxidase 4
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others GPX4 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Gpx4 (GPX4 Antibody Extrait)
Sujet

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

Synonyms: Glutathione peroxidase 4, GPX 4, GPX-4, GPX4, GPX4_HUMAN, GSHPx-4, MCSP, mitochondrial, PHGPx, Phospholipid hydroperoxidase, Phospholipid hydroperoxide glutathione peroxidase, Phospholipid hydroperoxide glutathione peroxidase, Phospholipid hydroperoxide glutathione peroxidase mitochondrial, snGPx, snPHGPx, Sperm nucleus glutathione peroxidase.

ID gène 2879
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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