Granzyme D/B/E/N/G/F/H anticorps (Alexa Fluor 488)

N° du produit ABIN899665

Détail du produit

Antigène: Granzyme D/B/E/N/G/F/H

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 488

Application: Western Blotting (WB)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Granzyme D/B/E/N/G/F/H

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Granzyme D/B/E/N/G/F/H

Sub Type: Cocktail

Sujet:

Synonyms: Granzyme D, Granzyme B, Granzyme E, Granzyme N, Granzyme G, Granzyme F, Granzyme H, Cathepsin G-like 2, CCP-X, CCP3, CCP4, CCP5, CGL-2, CSP-C, Ctla-5, Ctla-6, Ctla-7, CTLA1, CTSGL2, Grz d, Grz e, Grz f, Grz g, GZMD, Gzme, Gzmf, Gzmg, GZMH, MCSP-2, MCSP-3, MGC117682, Rnkp7, mast cell proteinase-3-like, Cytotoxic T-lymphocyte proteinase, Granzyme H precursor, Cytotoxic serine protease-C, CSP-C.

Background: protease required for lymphocyte cytotoxic granules to lyse target cells [RGD]. Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.

ID gène: 2999