Gremlin 1 (GREM1) (AA 130-170) anticorps (Alexa Fluor 647)

Détails pour le produit réf. ABIN899730, Fournisseur: Connectez-vous pour afficher
Antigène
  • grem1
  • MGC136702
  • zgc:136702
  • GREM1
  • drm
  • pig2
  • dand2
  • ihg-2
  • gremlin
  • Cktsf1b1
  • Drm
  • Grem
  • ld
  • gremlin-1
  • CKTSF1B1
  • DAND2
  • DRM
  • GREMLIN
  • IHG-2
  • cktsf1b1
  • gremlin 1a, DAN family BMP antagonist
  • gremlin 1, DAN family BMP antagonist
  • gremlin 1
  • gremlin 1, DAN family BMP antagonist L homeolog
  • grem1a
  • GREM1
  • LOC662541
  • grem1
  • Grem1
  • grem1.L
Épitope
AA 130-170
28
17
15
14
12
8
7
6
5
4
3
2
2
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
110
50
28
8
6
4
4
3
3
2
2
2
2
2
Hôte
Lapin
118
15
1
Clonalité
Polyclonal
Conjugué
Alexa Fluor 647
15
11
6
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
110
60
47
12
12
12
8
6
3
2
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène KLH conjugated synthetic peptide derived from human gremlin 1
Isotype IgG
Purification Purified by Protein A.
Antigène
Autre désignation Gremlin (GREM1 Antibody Extrait)
Sujet

Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis (By similarity).

Subcellular location: Secreted

Synonyms: DRM, HMPS, PIG2, CRAC1, DAND2, IHG-2, GREMLIN, CKTSF1B1, Gremlin-1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, Down-regulated in Mos-transformed cells protein, Increased in high glucose protein 2, GREM1
ID gène 26585
UniProt O60565
Pathways Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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