Grm2+Grm4 anticorps (Alexa Fluor 488)

Détails pour le produit réf. ABIN899782, Fournisseur: Connectez-vous pour afficher
Antigène
Reactivité
Humain, Souris, Rat (Rattus)
14
14
14
Hôte
Lapin
14
Clonalité
Polyclonal
Conjugué
Alexa Fluor 488
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
3
3
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène KLH conjugated synthetic peptide derived from human GRM2+GRM4
Isotype IgG
Purification Purified by Protein A.
Antigène
Sub Type Cocktail
Sujet

L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Synonyms: NULL

ID gène 2912
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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