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GZMB anticorps (AA 21-130) (Alexa Fluor 555)

GZMB Reactivité: Humain, Souris WB, FACS, IF (p), IF (cc) Hôte: Lapin Polyclonal Alexa Fluor 555
N° du produit ABIN900013
  • Antigène Voir toutes GZMB Anticorps
    GZMB (Granzyme B (GZMB))
    Épitope
    • 19
    • 15
    • 13
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-130
    Reactivité
    • 124
    • 52
    • 25
    • 10
    • 4
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 79
    • 48
    • 2
    Lapin
    Clonalité
    • 75
    • 54
    Polyclonal
    Conjugué
    • 81
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GZMB est conjugé à/à la Alexa Fluor 555
    Application
    • 71
    • 42
    • 39
    • 37
    • 19
    • 18
    • 18
    • 13
    • 12
    • 10
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Specificité
    Specific towards Granzyme B and Granzyme H
     Réactivité croisée
    Humain, Souris
    Homologie
    Rat,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GZMB
    Isotype
    IgG
    Top Product
    Discover our top product GZMB Anticorps primaire
  • Indications d'application
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GZMB (Granzyme B (GZMB))
    Autre désignation
    Granzyme B (GZMB Produits)
    Synonymes
    anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
    Sujet

    Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    ID gène
    3002
    UniProt
    P10144
    Pathways
    Apoptose, Caspase Cascade in Apoptosis
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