GZMB anticorps (AA 21-130) (Alexa Fluor 555)
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- Antigène Voir toutes GZMB Anticorps
- GZMB (Granzyme B (GZMB))
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Épitope
- AA 21-130
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GZMB est conjugé à/à la Alexa Fluor 555
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Specificité
- Specific towards Granzyme B and Granzyme H
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GZMB
- Isotype
- IgG
- Top Product
- Discover our top product GZMB Anticorps primaire
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- Indications d'application
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GZMB (Granzyme B (GZMB))
- Autre désignation
- Granzyme B (GZMB Produits)
- Synonymes
- anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
- Sujet
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Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
- ID gène
- 3002
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
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