Lamin B Receptor anticorps (AA 1-100) (Alexa Fluor 647)

N° du produit ABIN904408

Détail du produit anti-Lamin B Receptor anticorps (Alexa Fluor 647)

Antigène: Lamin B Receptor (LBR)

Épitope: AA 1-100

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B Receptor est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: The immunogen for this product has partial sequence similarity to SEPT8 and SEPT2

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Lamin B Receptor

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Lamin B Receptor

Antigène: Lamin B Receptor (LBR)

Autre désignation: Lamin B Receptor (LBR Produits)

Sujet:

Synonyms: PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR

Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

ID gène: 3930

UniProt: Q14739