PPARGC1A anticorps (AA 151-250) (AbBy Fluor® 555)

N° du produit ABIN910841

L’anticorps Lapin Polyclonal anti-PPARGC1A a été validé pour WB, FACS, IF (cc) et IF (p). Il convient pour détecter PPARGC1A dans des échantillons de Humain, Porc et Rat.

Aperçu rapide pour PPARGC1A anticorps (AA 151-250) (AbBy Fluor® 555) (ABIN910841)

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Reactivité: Humain, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1A est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PPARGC1A anticorps (AbBy Fluor® 555)

Épitope: AA 151-250

Réactivité croisée: Humain, Porc, Rat

Homologie: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGC1 alpha

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PPARGC1A

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Autre désignation: PGC1 alpha

Sujet:

Synonyms: LEM6, Ligand effect modulator 6, PERC, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1, Peroxisome prolerator activated receptor gamma coactivator 1 alpha, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-alpha, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC-1beta, PGC-1-alpha, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-alpha, PPAR-gamma coactivator 1-beta, PPARGC 1 alpha, PPARGC-1-alpha, PPARGC-1-beta, PPARGC1, PPARGC1A, Ppargc1b, PRGC1_HUMAN, PRGC2_HUMAN.

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq].

Poids moléculaire: 91-110kDa

ID gène: 10891

UniProt: Q9UBK2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Brown Fat Cell Differentiation