PPARGC1A anticorps (AA 151-250) (Biotin)

N° du produit ABIN910849

Cet anticorps Lapin Polyclonal détecte spécifiquement PPARGC1A dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain, Porc et Rat.

Aperçu rapide pour PPARGC1A anticorps (AA 151-250) (Biotin) (ABIN910849)

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Reactivité: Humain, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARGC1A est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PPARGC1A anticorps (Biotin)

Épitope: AA 151-250

Réactivité croisée: Humain, Porc, Rat

Homologie: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PGC1 alpha

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PPARGC1A

Antigène: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Autre désignation: PGC1 alpha

Sujet:

Synonyms: LEM6, Ligand effect modulator 6, PERC, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1, Peroxisome prolerator activated receptor gamma coactivator 1 alpha, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-alpha, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC-1beta, PGC-1-alpha, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-alpha, PPAR-gamma coactivator 1-beta, PPARGC 1 alpha, PPARGC-1-alpha, PPARGC-1-beta, PPARGC1, PPARGC1A, Ppargc1b, PRGC1_HUMAN, PRGC2_HUMAN.

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq].

Poids moléculaire: 91-110kDa

ID gène: 10891

UniProt: Q9UBK2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Brown Fat Cell Differentiation