PLSCR3 anticorps (AA 201-295) (Alexa Fluor 488)

N° du produit ABIN911528

Détail du produit anti-PLSCR3 anticorps (Alexa Fluor 488)

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Épitope: AA 201-295

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLSCR3 est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PLSCR3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PLSCR3

Antigène: PLSCR3 (phospholipid Scramblase 3 (PLSCR3))

Autre désignation: PLSCR3 (PLSCR3 Produits)

Synonymes: anticorps 2210403O21Rik, anticorps 2610037N06Rik, anticorps ESTM3, anticorps X83310, anticorps Pls3, anticorps zgc:77051, anticorps phospholipid scramblase 3, anticorps phospholipid scramblase 3b, anticorps PLSCR3, anticorps Plscr3, anticorps plscr3b

Sujet:

Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.

Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

ID gène: 57048

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis