Cathepsin K anticorps (Middle Region)

N° du produit ABIN926630

Détail du produit anti-Cathepsin K anticorps

Antigène: Cathepsin K (CTSK)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: CTSK antibody was raised in rabbit using the middle region of CTSK as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

CTSK Blocking Peptide, catalog no. 33R-8691, is also available for use as a blocking control in assays to test for specificity of this CTSK antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: CTSK (CTSK Produits)

Synonymes: anticorps CTS02, anticorps CTSO, anticorps CTSO1, anticorps CTSO2, anticorps PKND, anticorps PYCD, anticorps AI323530, anticorps MMS10-Q, anticorps Ms10q, anticorps catK, anticorps CTSK, anticorps wu:fa95f03, anticorps wu:fb08b05, anticorps zgc:110367, anticorps cts02, anticorps ctso, anticorps ctso1, anticorps ctso2, anticorps pknd, anticorps pycd, anticorps OC-2, anticorps catk, anticorps cathepsin K, anticorps cathepsin K L homeolog, anticorps Cathepsin K, anticorps CTSK, anticorps Ctsk, anticorps ctsk, anticorps ctsk.L, anticorps catk

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. Synonyms: Polyclonal CTSK antibody, Anti-CTSK antibody, cathepsin K antibody, CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, MGC23107 antibody, PKND antibody, PYCD antibody.

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades