TNFSF9 anticorps (C-Term)
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- Antigène Voir toutes TNFSF9 Anticorps
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNFSF9 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogène
- TNFSF9 antibody was raised in rabbit using the C terminal of TNFSF9 as the immunogen
- Top Product
- Discover our top product TNFSF9 Anticorps primaire
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- Indications d'application
- Optimal conditions should be determined by the investigator.
- Commentaires
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TNFSF9 Blocking Peptide, catalog no. 33R-8932, is also available for use as a blocking control in assays to test for specificity of this TNFSF9 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Antigène
- TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
- Autre désignation
- TNFSF9 (TNFSF9 Produits)
- Synonymes
- anticorps TNFSF9, anticorps 4-1BB-L, anticorps 4-1BBL, anticorps AI848817, anticorps Cd137l, anticorps Ly63l, anticorps CD137L, anticorps TNF superfamily member 9, anticorps tumor necrosis factor (ligand) superfamily, member 9, anticorps Tnfsf9, anticorps LOC476729, anticorps TNFSF9
- Sujet
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. Synonyms: Polyclonal TNFSF9 antibody, Anti-TNFSF9 antibody, tumor necrosis factor, ligand superfamily, member 9 antibody, 4-1BB-L antibody, CD137L antibody.
- Pathways
- Activated T Cell Proliferation, Cancer Immune Checkpoints
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