SPACA1 anticorps (N-Term)

N° du produit ABIN928305

Détail du produit anti-SPACA1 anticorps

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPACA1 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: SPACA1 antibody was raised in rabbit using the N terminal of SPACA1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SPACA1 Blocking Peptide, catalog no. 33R-9051, is also available for use as a blocking control in assays to test for specificity of this SPACA1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur SPACA1

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Autre désignation: SPACA1 (SPACA1 Produits)

Synonymes: anticorps SAMP32, anticorps 1700124L11Rik, anticorps 4930540L03Rik, anticorps sperm acrosome associated 1, anticorps SPACA1, anticorps Spaca1

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. Synonyms: Polyclonal SPACA1 antibody, Anti-SPACA1 antibody, sperm acrosome associated 1 antibody, MGC32952 antibody, SAMP32 antibody.