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USP20 anticorps (Middle Region)

USP20 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN929196
  • Antigène Voir toutes USP20 Anticorps
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 42
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 4
    • 1
    Lapin
    Clonalité
    • 42
    • 1
    Polyclonal
    Conjugué
    • 22
    • 5
    • 4
    • 4
    • 4
    • 4
    Cet anticorp USP20 est non-conjugé
    Application
    • 30
    • 26
    • 17
    • 4
    • 4
    Western Blotting (WB)
    Purification
    Purified
    Immunogène
    USP20 antibody was raised in rabbit using the middle region of USP20 as the immunogen
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    Discover our top product USP20 Anticorps primaire
  • Indications d'application
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Antigène
    USP20 (Ubiquitin Specific Peptidase 20 (USP20))
    Autre désignation
    USP20 (USP20 Produits)
    Synonymes
    anticorps USP20, anticorps vdu2, anticorps lsfr3a, anticorps LSFR3A, anticorps VDU2, anticorps hVDU2, anticorps 1700055M05Rik, anticorps AI467231, anticorps Vdu2, anticorps im:7151955, anticorps zgc:63661, anticorps universal stress protein, anticorps ubiquitin specific peptidase 20, anticorps ubiquitin specific peptidase 20 L homeolog, anticorps RR_RS15875, anticorps USP20, anticorps usp20, anticorps Usp20, anticorps usp20.L
    Sujet
    USP20 is a deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling.USP20 acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). USP20 plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Synonyms: Polyclonal USP20 antibody, Anti-USP20 antibody, ubiquitin specific peptidase 20 antibody, KIAA1003 antibody, LSFR3A antibody, VDU2 antibody.
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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