CTSC anticorps (Middle Region)

N° du produit ABIN929442

Détail du produit anti-CTSC anticorps

Antigène: CTSC (Cathepsin C (CTSC))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: CTSC antibody was raised in rabbit using the middle region of CTSC as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CTSC Blocking Peptide, catalog no. 33R-10021, is also available for use as a blocking control in assays to test for specificity of this CTSC antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC (CTSC Produits)

Synonymes: anticorps CPPI, anticorps DPP-I, anticorps DPP1, anticorps DPPI, anticorps HMS, anticorps JP, anticorps JPD, anticorps PALS, anticorps PDON1, anticorps PLS, anticorps MGC69126, anticorps MGC107782, anticorps AI047818, anticorps CATC, anticorps cb912, anticorps ik:tdsubc_1h2, anticorps sb:cb146, anticorps wu:fb34g12, anticorps wu:fj58d01, anticorps cathepsin C, anticorps cathepsin C L homeolog, anticorps cathepsin CPC1, anticorps CTSC, anticorps ctsc.L, anticorps ctsc, anticorps TP03_0357, anticorps CMU_003360, anticorps CPC1, anticorps NAEGRDRAFT_80477, anticorps NAEGRDRAFT_37577, anticorps Ctsc, anticorps Smp_183330

Sujet: CTSC is a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in CTSC have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Synonyms: Polyclonal CTSC antibody, Anti-CTSC antibody, cathepsin C antibody, CPPI antibody, DPP1 antibody, DPPI antibody, HMS antibody, JP antibody, JPD antibody, PALS antibody, PLS antibody.