CYP3A5 anticorps (N-Term)

N° du produit ABIN929450

Détail du produit anti-CYP3A5 anticorps

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP3A5 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: CYP3 A5 antibody was raised in rabbit using the N terminal of CYP3 5 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CYP3A5 Blocking Peptide, catalog no. 33R-1283, is also available for use as a blocking control in assays to test for specificity of this CYP3A5 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CYP3A5

Antigène: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Autre désignation: CYP3A5 (CYP3A5 Produits)

Synonymes: anticorps CP35, anticorps CYPIIIA5, anticorps P450PCN3, anticorps PCN3, anticorps cytochrome P450 family 3 subfamily A member 5, anticorps CYP3A5

Sujet: This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. Synonyms: Polyclonal CYP3A5 antibody, Anti-CYP3A5 antibody, cytochrome P450, family 3, subfamily A, polypeptide 5 antibody, CP35 antibody, P450PCN3 antibody, PCN3 antibody.

Pathways: Steroid Hormone Biosynthesis