PRKAR1 A antibody was raised in mouse using recombinant Human Protein Kinase, Camp-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1) (Prkar1 )
PRKAR1A
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 0.2-2 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
PRKAR1 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
Antigène
PRKAR1A
(Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))
CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMPdependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Synonyms: Monoclonal PRKAR1A antibody, Anti-PRKAR1A antibody, Protein kinase cAMP dependent regulatory type I alpha antibody, CAR antibody, CNC antibody, CNC1 antibody, PKR1 antibody, TSE1 antibody, PPNAD1 antibody, PRKAR1 antibody, MGC17251 antibody, DKFZp779L0468 antibody.