SEMA7A anticorps (FITC)
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- Antigène Voir toutes SEMA7A Anticorps
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SEMA7A est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS)
- Specificité
- The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.
- Réactivité croisée (Details)
- Human
- Purification
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- HPB-ALL human T cell line
- Clone
- MEM-150
- Isotype
- IgM
- Top Product
- Discover our top product SEMA7A Anticorps primaire
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- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
- Commentaires
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Reconstitution
- No reconstitution is necessary.
- Buffer
- Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
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Do not freeze.
Avoid prolonged exposure to light. - Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." dans: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).
: "Evidence that CDw108 membrane protein bears the JMH blood group antigen." dans: Transfusion, Vol. 35, Issue 7, pp. 566-70, (1995) (PubMed).
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Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." dans: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).
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- Antigène
- SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
- Autre désignation
- CD108 (SEMA7A Produits)
- Synonymes
- anticorps 2900057C09Rik, anticorps CDw108, anticorps H-Sema-L, anticorps M-Sema-L, anticorps Semal, anticorps CD108, anticorps H-SEMA-K1, anticorps JMH, anticorps SEMAK1, anticorps SEMAL, anticorps sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A, anticorps semaphorin 7A (John Milton Hagen blood group), anticorps Sema7a, anticorps SEMA7A
- Sujet
- Semaphorin 7A (John Milton Hagen blood group),CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors –, plexin C1 and beta1 integrins.,Semaphorin 7a, JMH blood group antigen, SEMAL, SEMAK1
- ID gène
- 8482
- UniProt
- O75326
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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