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CD2 anticorps

CD2 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-65 unconjugated
N° du produit ABIN94021
  • Antigène Voir toutes CD2 Anticorps
    CD2
    Reactivité
    • 168
    • 36
    • 17
    • 16
    • 12
    • 10
    • 10
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 138
    • 44
    • 24
    • 2
    Souris
    Clonalité
    • 163
    • 43
    • 2
    Monoclonal
    Conjugué
    • 86
    • 24
    • 22
    • 18
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD2 est non-conjugé
    Application
    • 148
    • 53
    • 52
    • 36
    • 34
    • 32
    • 22
    • 13
    • 11
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificité
    The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Human peripheral T cells.
    Clone
    MEM-65
    Isotype
    IgG1
    Top Product
    Discover our top product CD2 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Espagnolle, Depoil, Zaru, Demeur, Champagne, Guiraud, Valitutti: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." dans: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).

    Drbal, Hilgert, Cebecauer, Angelisová, Horejsí: "New monoclonal antibodies to human leucocyte surface molecule CD2." dans: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).

  • Antigène
    CD2
    Autre désignation
    CD2 (CD2 Produits)
    Synonymes
    anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2
    Sujet
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
    ID gène
    914
    UniProt
    P06729
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