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CD33 anticorps (Biotin)

CD33 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal HIM3-4 Biotin
N° du produit ABIN94073
  • Antigène Voir toutes CD33 Anticorps
    CD33
    Reactivité
    • 173
    • 35
    • 15
    • 13
    • 6
    • 6
    • 3
    • 1
    Humain, Non-Human Primate
    Hôte
    • 100
    • 79
    Souris
    Clonalité
    • 95
    • 83
    • 1
    Monoclonal
    Conjugué
    • 60
    • 17
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    • 3
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Cet anticorp CD33 est conjugé à/à la Biotin
    Application
    • 108
    • 106
    • 45
    • 35
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    Flow Cytometry (FACS)
    Specificité
    The antibody HIM3-4 reacts with an extracellular epitope of CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    Immunogène
    NFMY-9s human cell line
    Clone
    HIM3-4
    Isotype
    IgG1
    Top Product
    Discover our top product CD33 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-12 μg/mL
    Commentaires

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • McCormack, Muji?, Osdal, Bruserud, Gjertsen: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." dans: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).

  • Antigène
    CD33
    Autre désignation
    CD33 (CD33 Produits)
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
    Sujet
    CD33 Molecule,CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.,SIGLEC3, p67
    ID gène
    945
    UniProt
    P20138
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