Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CD34 anticorps

CD34 Reactivité: Humain FACS, WB, IHC (p), ICC Hôte: Souris Monoclonal 4H11[APG] unconjugated
N° du produit ABIN94077
  • Antigène Voir toutes CD34 Anticorps
    CD34
    Reactivité
    • 312
    • 115
    • 105
    • 33
    • 19
    • 18
    • 17
    • 17
    • 16
    • 16
    • 9
    • 6
    • 6
    • 1
    • 1
    Humain
    Hôte
    • 182
    • 145
    • 22
    • 6
    • 4
    Souris
    Clonalité
    • 240
    • 116
    • 2
    Monoclonal
    Conjugué
    • 131
    • 29
    • 28
    • 23
    • 18
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD34 est non-conjugé
    Application
    • 241
    • 207
    • 92
    • 67
    • 62
    • 52
    • 39
    • 37
    • 34
    • 28
    • 24
    • 19
    • 13
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody 4H11[APG] reacts with extracellular class III epitope on CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of class III antibodies BIRMA K3 and 8G12 on KG1a cell line.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia.
    Clone
    4H11[APG]
    Isotype
    IgG1
    Top Product
    Discover our top product CD34 Anticorps primaire
  • Indications d'application
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: Kg-1a, TF-1 cells, non-reducing conditions.
    Flow cytometry: Recommended dilution: 2 μg/mL.
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: placenta endothelium.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Elknerová, Lacinová, Soucek, Marinov, Stöckbauer: "Growth inhibitory effect of the antibody to hematopoietic stem cell antigen CD34 in leukemic cell lines." dans: Neoplasma, Vol. 54, Issue 4, pp. 311-20, (2007) (PubMed).

  • Antigène
    CD34
    Autre désignation
    CD34 (CD34 Produits)
    Synonymes
    anticorps AU040960, anticorps CD34 molecule, anticorps CD34 antigen, anticorps CD34, anticorps Cd34
    Sujet
    CD34 Molecule,CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
    ID gène
    947
    UniProt
    P28906
Vous êtes ici:
Support technique