CD8 anticorps
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- Antigène Voir toutes CD8 Anticorps
- CD8
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD8 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificité
- The antibody MEM-87 recognizes an extracellular epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 kDa).
- Réactivité croisée (Details)
- Human
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Leukocytes of a patient suffering from LGL Type Leukemia.
- Clone
- MEM-87
- Isotype
- IgG1
- Top Product
- Discover our top product CD8 Anticorps primaire
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anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reactivité: Humain, Souris, Rat FACS, IHC (fro), WB, ELISA, IHC (p), IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-CD8 (CD8) antibodyCD8 Reactivité: Humain FACS, IP, CyTOF Hôte: Souris Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (Biotin)CD8 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibody (FITC)CD8 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibodyCD8 Reactivité: Humain IHC, WB, IP, ELISA Hôte: Lapin Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD8 (CD8) antibody (PE)CD8 Reactivité: Cat FACS Hôte: Souris Monoclonal fCD8 PE
anti-CD8 (CD8) antibody (PerCP)CD8 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-31 PerCP
anti-CD8 (CD8) antibody (APC)CD8 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-31 APC
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- Indications d'application
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Flow cytometry: Recommended dilution: 2 μg/mL.
Immunoprecipitation: Excellent for immunoisolation of CD8 positive T cells. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- CD8
- Autre désignation
- CD8 (CD8 Produits)
- Synonymes
- anticorps CD8, anticorps Leu2, anticorps MAL, anticorps p32, anticorps CD8a molecule, anticorps CD8A
- Sujet
- The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as alpha/beta heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as alpha/alpha homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha-beta but not alpha-alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.,p32, LEU2
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