AKR1C2 anticorps (C-Term)

N° du produit ABIN950320

Détail du produit anti-AKR1C2 anticorps

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Épitope: AA 295-323, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to AKR1C2.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 295-323 amino acids from the C-terminal region of human AKR1C2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AKR1C2

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Autre désignation: AKR1C2 / DDH2 (AKR1C2 Produits)

Synonymes: anticorps AKR1C-pseudo, anticorps BABP, anticorps DD, anticorps DD2, anticorps DDH2, anticorps HAKRD, anticorps HBAB, anticorps MCDR2, anticorps SRXY8, anticorps Akr1c21, anticorps aldo-keto reductase family 1 member C2, anticorps aldo-keto reductase family 1, member C2, anticorps AKR1C2, anticorps Akr1c2

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.Synonyms: 2-dihydrobenzene-1, 2-diol dehydrogenase, 3-alpha-HSD3, Aldo-keto reductase family 1 member C2, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, Dihydrodiol dehydrogenase/bile acid-binding protein, Trans-1, Type III 3-alpha-hydroxysteroid dehydrogenase

Poids moléculaire: 36735 Da

ID gène: 1646

NCBI Accession: NP_001345

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process