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CARD16 anticorps (N-Term)

CARD16 Reactivité: Humain WB, FACS, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN951040
  • Antigène Voir toutes CARD16 Anticorps
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    Épitope
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 44-73, N-Term
    Reactivité
    Humain
    Hôte
    • 21
    • 4
    • 1
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CARD16 est non-conjugé
    Application
    • 15
    • 13
    • 8
    • 4
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to COP1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human COP1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CARD16 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    Autre désignation
    CARD16 / COP1 (CARD16 Produits)
    Synonymes
    anticorps COP, anticorps COP1, anticorps PSEUDO-ICE, anticorps caspase recruitment domain family member 16, anticorps CARD16
    Sujet
    Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.Synonyms: CARD only domain-containing protein 1, Caspase recruitment domain-containing protein 16, Caspase-1 inhibitor COP, PSEUDO-ICE, Pseudo interleukin-1 beta converting enzyme
    Poids moléculaire
    22625 Da
    ID gène
    114769
    NCBI Accession
    NP_001017534
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