DDX11 anticorps (Middle Region)

N° du produit ABIN951862

Détail du produit anti-DDX11 anticorps

Antigène: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Épitope: AA 663-691, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX11 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse DEAD box protein 11 (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 663-691 amino acids from the Central region of Human DDX11.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-DDX11 (ABIN951862)

Farina, Shin, Kim, Bermudez, Kelman, Seo, Hurwitz: "Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1." dans: The Journal of biological chemistry, Vol. 283, Issue 30, pp. 20925-36, (2008) (PubMed).

Détails sur DDX11

Antigène: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Autre désignation: DDX11 (DDX11 Produits)

Synonymes: anticorps CHL1, anticorps CHLR1, anticorps KRG2, anticorps WABS, anticorps 4732462I11Rik, anticorps essa15a, anticorps putative ATP-dependent RNA helicase DDX11-like protein 8, anticorps DEAD/H-box helicase 11, anticorps DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11, anticorps LOC100448472, anticorps DDX11, anticorps Ddx11

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability.Synonyms: CHL1, CHLR1, DEAD box protein 11, DEAD/H box protein 11, KRG-2, KRG2, Keratinocyte growth factor-regulated gene 2 protein, Probable ATP-dependent RNA helicase DDX11

Poids moléculaire: 108313 Da

ID gène: 1663

NCBI Accession: NP_004390

Pathways: ER-Nucleus Signaling