MYSM1 anticorps (N-Term)

N° du produit ABIN953592

Détail du produit anti-MYSM1 anticorps

Antigène: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Épitope: AA 118-147, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYSM1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes MYSM1 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 118-147aa) of human MYSM1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-MYSM1 (ABIN953592)

Dephoure, Zhou, Villén, Beausoleil, Bakalarski, Elledge, Gygi: "A quantitative atlas of mitotic phosphorylation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, (2008) (PubMed).

Détails sur MYSM1

Antigène: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Autre désignation: MYSM1 (MYSM1 Produits)

Synonymes: anticorps 2A-DUB, anticorps 2ADUB, anticorps RP4-592A1.1, anticorps C130067A03Rik, anticorps C530050H10Rik, anticorps RGD1311787, anticorps 2adub, anticorps Myb like, SWIRM and MPN domains 1, anticorps myb-like, SWIRM and MPN domains 1, anticorps Myb like, SWIRM and MPN domains 1 L homeolog, anticorps MYSM1, anticorps Mysm1, anticorps mysm1.L

Sujet: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Synonyms: Histone H2A deubiquitinase MYSM1, KIAA1915, Myb-like SWIRM and MPN domain-containing protein 1

ID gène: 114803

NCBI Accession: NP_001078956

Pathways: Chromatin Binding