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PRKAA2 anticorps (Middle Region, Thr172)

PRKAA2 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN954298
  • Antigène Voir toutes PRKAA2 Anticorps
    PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
    Épitope
    • 16
    • 16
    • 13
    • 12
    • 10
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 148-177, Middle Region, Thr172
    Reactivité
    • 127
    • 57
    • 47
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 115
    • 12
    • 3
    • 1
    Lapin
    Clonalité
    • 108
    • 23
    Polyclonal
    Conjugué
    • 58
    • 12
    • 10
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PRKAA2 est non-conjugé
    Application
    • 116
    • 62
    • 41
    • 33
    • 26
    • 26
    • 15
    • 15
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to PRKAA2.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 148-177 amino acids from the Central region of human PRKAA2 (Thr172)
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PRKAA2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
    Autre désignation
    PRKAA2 (PRKAA2 Produits)
    Synonymes
    anticorps AMPK, anticorps AMPK2, anticorps AMPKa2, anticorps PRKAA, anticorps Ampk, anticorps Ampka2, anticorps 2310008I11Rik, anticorps A830082D05, anticorps AMPKalpha2, anticorps AMPKA2, anticorps ampk, anticorps ampk2, anticorps prkaa, anticorps prkaa1, anticorps PRKAA2, anticorps protein kinase AMP-activated catalytic subunit alpha 2, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit, anticorps protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog, anticorps PRKAA2, anticorps Prkaa2, anticorps prkaa2.S, anticorps prkaa2
    Sujet
    The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2, AMPK alpha-2 chain, AMPK2
    Poids moléculaire
    62320 Da
    ID gène
    5563
    NCBI Accession
    NP_006243
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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