RHOB anticorps (Middle Region)

N° du produit ABIN954540

Détail du produit anti-RHOB anticorps

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Épitope: AA 103-137, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOB est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to RhoB.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogène: KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human ARHB

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RHOB

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Autre désignation: RhoB (RHOB Produits)

Synonymes: anticorps ARH6, anticorps ARHB, anticorps MST081, anticorps MSTP081, anticorps RHOH6, anticorps AA017882, anticorps Arh6, anticorps Arhb, anticorps RHO, anticorps arha, anticorps rhoa, anticorps wu:fj42e08, anticorps zgc:92206, anticorps rhob, anticorps xrhob, anticorps ras homolog family member B, anticorps ras homolog gene family, member Ab, anticorps ras homolog family member B S homeolog, anticorps RHOB, anticorps Rhob, anticorps rhoab, anticorps rhob.S

Sujet: ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.Synonyms: ARH6, ARHB, Rho cDNA clone 6, Rho-related GTP-binding protein RhoB

ID gène: 388

NCBI Accession: NP_004031