TAF1 anticorps (C-Term)

N° du produit ABIN955063

Cet anticorps Lapin Polyclonal détecte spécifiquement TAF1 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour TAF1 anticorps (C-Term) (ABIN955063)

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-TAF1 anticorps

Épitope: AA 1860-1893, C-Term

Specificité: This antibody reacts to TAF1.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 1860-1893 amino acids from the C-terminal region of human TAF1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TAF1

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Autre désignation: TAF1

Sujet: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.Synonyms: BA2R, CCG1, CCGS, Cell cycle gene 1 protein, TAFII250, TBP-associated factor 250 kDa, Transcription initiation factor TFIID 250 kDa subunit, Transcription initiation factor TFIID subunit 1

Poids moléculaire: 106kd Isoform 2. 212677 Da

ID gène: 6872

NCBI Accession: NP_004597