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USP28 anticorps (Internal Region)

USP28 Reactivité: Humain, Boeuf (Vache) IHC (p), EIA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN955488
  • Antigène Voir toutes USP28 Anticorps
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Internal Region
    Reactivité
    • 48
    • 17
    • 2
    • 1
    • 1
    Humain, Boeuf (Vache)
    Hôte
    • 60
    • 2
    • 1
    Chèvre
    Clonalité
    • 62
    • 1
    Polyclonal
    Conjugué
    • 20
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp USP28 est non-conjugé
    Application
    • 39
    • 26
    • 13
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Séquence
    C-SVELKHYIQE DN
    Specificité
    Recognizes USP28
    Réactivité croisée (Details)
    Species reactivity (expected):Cow.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    Immunogène
    Peptide with sequence from the internal region of the protein sequence according to NP_065937.1. Genename: USP28
    Top Product
    Discover our top product USP28 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    USP28 (Ubiquitin Specific Peptidase 28 (USP28))
    Autre désignation
    USP28 (USP28 Produits)
    Synonymes
    anticorps im:7138195, anticorps USP28, anticorps 9830148O20Rik, anticorps AU022237, anticorps mKIAA1515, anticorps ubiquitin specific peptidase 28, anticorps USP28, anticorps usp28, anticorps Usp28
    Sujet
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 28, KIAA1515, Ubiquitin carboxyl-terminal hydrolase 28, Ubiquitin thioesterase 28, Ubiquitin-specific-processing protease 28
    ID gène
    57646
    NCBI Accession
    NP_065937
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