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FOXD3 anticorps

FOXD3 Reactivité: Humain, Souris, Singe WB, ELISA Hôte: Souris Monoclonal 5G9 unconjugated
N° du produit ABIN966161
  • Antigène Voir toutes FOXD3 Anticorps
    FOXD3 (Forkhead Box D3 (FOXD3))
    Reactivité
    • 31
    • 24
    • 5
    • 2
    • 2
    • 2
    • 2
    Humain, Souris, Singe
    Hôte
    • 29
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 31
    • 2
    Monoclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FOXD3 est non-conjugé
    Application
    • 15
    • 13
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human FOXD3 expressed in E. Coli.
    Clone
    5G9
    Isotype
    IgG1
    Top Product
    Discover our top product FOXD3 Anticorps primaire
  • Indications d'application
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Saleem, Banerjee-Basu, Berry, Baxevanis, Walter: "Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1." dans: American journal of human genetics, Vol. 68, Issue 3, pp. 627-41, (2001) (PubMed).

    Hromas, Moore, Johnston, Socha, Klemsz: "Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells." dans: Blood, Vol. 81, Issue 11, pp. 2854-9, (1993) (PubMed).

  • Antigène
    FOXD3 (Forkhead Box D3 (FOXD3))
    Autre désignation
    FOXD3 (FOXD3 Produits)
    Synonymes
    anticorps AIS1, anticorps Genesis, anticorps HFH2, anticorps VAMAS2, anticorps CWH3, anticorps Hfh2, anticorps fkd6, anticorps fkh6, anticorps forkhead-6, anticorps zgc:111934, anticorps XFD-6, anticorps xfoxd3, anticorps FOXD3, anticorps genesis, anticorps hfh2, anticorps foxd3b, anticorps foxd3b-A, anticorps forkhead box D3, anticorps forkhead box D3 L homeolog, anticorps forkhead box D3 S homeolog, anticorps FOXD3, anticorps Foxd3, anticorps foxd3, anticorps foxd3.L, anticorps foxd3.S
    Sujet
    FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation . FoxD3 is required for the maintenance of the mammalian neural crest, FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures . FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis .
    Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined .
    Synonyms: AIS1, HFH2, Genesis, FOXD3
    Poids moléculaire
    48kDa
    ID gène
    27022
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