MSH6 anticorps
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- Antigène Voir toutes MSH6 Anticorps
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MSH6 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of MSH6 expressed in E. Coli.
- Clone
- 3A10H7
- Isotype
- IgG1
- Top Product
- Discover our top product MSH6 Anticorps primaire
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- Indications d'application
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
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Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
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Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).
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- Antigène
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Autre désignation
- MSH6 (MSH6 Produits)
- Synonymes
- anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6
- Sujet
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Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
Synonyms: GTBP, HSAP, HNPCC5 - ID gène
- 2956
- Pathways
- Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
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