OCT4 anticorps (POU Class 5 Homeobox 1)

Details for Product anti-POU5F1 Antibody No. ABIN966710, Fournisseur: Connectez-vous pour afficher
Antigène
  • OCT3
  • OCT4
  • OTF-3
  • OTF3
  • OTF4
  • Oct-3
  • Oct-4
  • POU5F1
  • gp9
  • gp-9
  • oct4
  • pou2
  • POU-2
  • cb197
  • spg/pou2
  • chunp6868
  • wu:fd18d06
  • NF-A3
  • Oct-3/4
  • Oct3
  • Oct3/4
  • Oct4
  • Otf-3
  • Otf-4
  • Otf3
  • Otf3-rs7
  • Otf3g
  • Otf4
  • POU class 5 homeobox 1
  • POU domain, class 5, transcription factor 3
  • POU domain, class 5, transcription factor 1
  • POU5F1
  • pou5f3
  • Pou5f1
Reactivité
Humain
396
176
68
25
17
14
13
13
9
6
5
2
2
2
2
1
1
1
1
Hôte
Souris
226
147
32
31
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp OCT4 est non-conjugé
18
14
12
12
11
8
7
6
5
5
4
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
332
176
111
107
78
74
48
18
17
13
7
6
4
3
3
3
2
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Purified recombinant fragment of OCT4 expressed in E. Coli.
Clone 3A5
Isotype IgG1
Purification Ascitic fluid
Autre désignation OCT4 (POU5F1 Antibody Extrait)
Sujet Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in proteinprotein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation. Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.
Synonyms: OCT3, POU5F1
Poids moléculaire 39kDa
ID gène 5460
Pathways Stem Cell Maintenance
Indications d'application Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Produit citée dans: Sommer, Stadtfeld, Murphy, Hochedlinger, Kotton, Mostoslavsky: "Induced pluripotent stem cell generation using a single lentiviral stem cell cassette." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 3, pp. 543-9, 2009 (PubMed).

Ettwiller, Budd, Spitz, Wittbrodt: "Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences." dans: Genome biology, Vol. 9, Issue 12, pp. R172, 2009 (PubMed).

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