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OGG1 anticorps (acLys338, acLys341, C-Term)

OGG1 Reactivité: Humain IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966716
  • Antigène Voir toutes OGG1 Anticorps
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    Épitope
    • 16
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    acLys338, acLys341, C-Term
    Reactivité
    • 51
    • 25
    • 24
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 48
    • 5
    • 1
    Lapin
    Clonalité
    • 43
    • 11
    Polyclonal
    Conjugué
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OGG1 est non-conjugé
    Application
    • 39
    • 14
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogène
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human OGG1 (N-glycosylase/DNA lyase)
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    Discover our top product OGG1 Anticorps primaire
  • Restrictions
    For Research Use only
  • Stock
    4 °C
  • Aburatani, Hippo, Ishida, Takashima, Matsuba, Kodama, Takao, Yasui, Yamamoto, Asano: "Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue." dans: Cancer research, Vol. 57, Issue 11, pp. 2151-6, (1997) (PubMed).

    Rosenquist, Zharkov, Grollman: "Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 14, pp. 7429-34, (1997) (PubMed).

    Roldán-Arjona, Wei, Carter, Klungland, Anselmino, Wang, Augustus, Lindahl: "Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 15, pp. 8016-20, (1997) (PubMed).

    Kuo, Sklar: "Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers." dans: The Journal of experimental medicine, Vol. 186, Issue 9, pp. 1547-56, (1997) (PubMed).

    Bjorâs, Luna, Johnsen, Hoff, Haug, Rognes, Seeberg: "Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites." dans: The EMBO journal, Vol. 16, Issue 20, pp. 6314-22, (1997) (PubMed).

  • Antigène
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    Autre désignation
    OGG1 (OGG1 Produits)
    Synonymes
    anticorps OGG1, anticorps zgc:158858, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, anticorps ATOGG1, anticorps F8K7.14, anticorps F8K7_14, anticorps 19.m02329, anticorps DDBDRAFT_0184479, anticorps DDBDRAFT_0233024, anticorps DDB_0184479, anticorps DDB_0233024, anticorps ogg1, anticorps Tb04.1H19.930, anticorps HMMH, anticorps HOGG1, anticorps MUTM, anticorps OGH1, anticorps Mmh, anticorps 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA glycosylase L homeolog, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps 8-OXOGUANINE DNA GLYCOSYLASE, anticorps putative 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA-glycosylase, anticorps N-glycosylase/DNA lyase OGG1, anticorps 8-oxoguanine DNA-glycosylase 1, anticorps OGG1, anticorps ogg1.L, anticorps ogg1, anticorps ECU08_0770, anticorps CA_C2707, anticorps BBOV_I004290, anticorps Smp_074010.1, anticorps LOC9329243, anticorps Tb927.4.2480, anticorps Ogg1
    Sujet
    DNA repair enzyme that incises DNA at 8-oxoG residues. OGG1 (N-glycosylase/DNA lyase) excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-Nmethylformamidopyrimidine (FAPY) from damaged DNA. OGG1 has a beta-lyase activity that nicks DNA 3' to the lesion. Defects in OGG1 are associated with tumor formation.Defects in OGG1 are a cause of renal cell carcinoma OGG1 belongs to the type-1 OGG1 family.
    Synonyms: MMH, MUTM, OGH1
    Pathways
    Réparation de l'ADN
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