p53 anticorps (Tumor Protein P53) (pSer15)

Details for Product anti-TP53 Antibody No. ABIN966755, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Épitope
pSer15
169
125
78
72
71
71
70
59
58
54
51
46
45
43
36
34
34
25
24
24
22
22
21
21
17
15
15
15
15
15
15
15
13
13
13
12
11
10
9
9
8
8
8
8
7
7
7
7
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
2533
566
476
308
162
104
103
67
56
26
23
23
18
17
17
16
7
6
5
4
4
4
4
3
3
2
2
1
1
Hôte
Lapin
1480
1169
7
5
1
1
1
1
Conjugué
Cet anticorp p53 est non-conjugé
82
81
69
51
44
38
37
32
23
23
23
20
20
20
20
20
19
19
18
18
17
16
15
14
14
14
14
14
12
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
2
2
2
Application
Immunohistochemistry (IHC)
2091
963
864
784
682
663
421
317
267
179
110
90
75
41
32
17
17
15
13
10
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 15 (P-L-SP-Q-E).
Specificité P53 (phospho-Ser15) antibody detects endogenous levels of p53 only when phosphorylated at serine15.
Plasmids, Primers & others Plasmids, Primers & others p53 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation p53 (TP53 Antibody Extrait)
Pathways Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Hirao, Kong, Matsuoka, Wakeham, Ruland, Yoshida, Liu, Elledge, Mak: "DNA damage-induced activation of p53 by the checkpoint kinase Chk2." dans: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1824-7, 2000 (PubMed).

Honda, Tanaka, Yasuda: "Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53." dans: FEBS letters, Vol. 420, Issue 1, pp. 25-7, 1998 (PubMed).

Produit citée dans: Shieh, Taya, Prives: "DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization." dans: The EMBO journal, Vol. 18, Issue 7, pp. 1815-23, 1999 (PubMed).

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