p53 anticorps (Tumor Protein P53) (pSer46)

Details for Product anti-TP53 Antibody No. ABIN966757, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Épitope
pSer46
167
119
77
76
73
72
66
59
59
57
47
44
42
38
34
34
33
24
24
23
23
22
21
21
17
15
15
15
15
15
15
15
14
13
13
12
11
10
9
9
9
8
8
8
7
7
7
7
7
7
6
6
6
6
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
2512
582
483
295
154
105
103
61
55
24
23
22
17
16
14
14
7
6
5
4
4
4
4
3
3
3
2
1
1
Hôte
Lapin
1505
1128
7
5
1
1
1
1
Conjugué
Cet anticorp p53 est non-conjugé
79
79
67
52
45
36
34
32
23
23
21
20
19
19
19
19
18
18
18
18
15
14
14
12
12
12
12
12
11
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
2
2
2
Application
Immunohistochemistry (IHC)
2085
959
864
777
667
647
422
294
260
155
110
90
75
41
32
19
16
15
13
6
4
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
Specificité P53 (phospho-Ser46) antibody detects endogenous levels of p53 only when phosphorylated at serine 46.
Plasmids, Primers & others Plasmids, Primers & others p53 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation p53 (TP53 Antibody Extrait)
Pathways Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Di Stefano, Soddu, Sacchi, DOrazi: "HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage." dans: Oncogene, Vol. 24, Issue 35, pp. 5431-42, 2005 (PubMed).

Dhavan, Tsai: "A decade of CDK5." dans: Nature reviews. Molecular cell biology, Vol. 2, Issue 10, pp. 749-59, 2001 (PubMed).

Patrick, Zhou, Kwon, Howley, Tsai: "p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway." dans: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24057-64, 1998 (PubMed).

Produit citée dans: Mayo, Seo, Jackson, Smith, Rivera Guzman, Korgaonkar, Donner: "Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified." dans: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 25953-9, 2005 (PubMed).

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