p53 anticorps (Tumor Protein P53) (pSer46)

Details for Product anti-TP53 Antibody No. ABIN966757, Fournisseur: Connectez-vous pour afficher
Antigène
  • BCC7
  • LFS1
  • P53
  • TRP53
  • p53
  • Trp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • tp53
  • Xp53
  • TP53
  • tumor protein p53
  • cellular tumor antigen p53
  • transformation related protein 53
  • tumor protein p53 L homeolog
  • TP53
  • CpipJ_CPIJ002758
  • Tp53
  • tp53
  • Trp53
  • tp53.L
Épitope
pSer46
187
123
89
86
76
74
69
60
58
53
51
46
45
44
44
34
34
34
25
23
22
22
22
22
17
15
15
15
15
15
15
14
14
13
12
11
11
11
10
9
9
8
8
8
8
8
7
7
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
2647
572
481
303
155
120
119
87
52
23
22
19
19
16
14
13
6
5
4
4
3
3
3
1
1
Hôte
Lapin
1491
1283
7
1
1
1
1
Conjugué
Cet anticorp p53 est non-conjugé
88
85
74
61
54
46
45
35
32
31
31
25
25
25
25
24
24
24
20
19
18
18
18
14
14
14
14
14
12
8
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
6
5
2
2
2
Application
Immunohistochemistry (IHC)
2176
973
893
804
782
752
425
348
311
179
110
90
75
41
34
18
17
15
13
13
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
Specificité P53 (phospho-Ser46) antibody detects endogenous levels of p53 only when phosphorylated at serine 46.
Plasmids, Primers & others Plasmids, Primers & others p53 products on genomics-online (e.g. as negative or positive controls)
Autre désignation p53 (TP53 Antibody Extrait)
Pathways Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Di Stefano, Soddu, Sacchi, DOrazi: "HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage." dans: Oncogene, Vol. 24, Issue 35, pp. 5431-42, 2005 (PubMed).

Dhavan, Tsai: "A decade of CDK5." dans: Nature reviews. Molecular cell biology, Vol. 2, Issue 10, pp. 749-59, 2001 (PubMed).

Patrick, Zhou, Kwon, Howley, Tsai: "p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway." dans: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24057-64, 1998 (PubMed).

Produit citée dans: Mayo, Seo, Jackson, Smith, Rivera Guzman, Korgaonkar, Donner: "Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified." dans: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 25953-9, 2005 (PubMed).

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