DOK1 anticorps (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1)) (pTyr398)

Details for Product anti-DOK1 Antibody No. ABIN966765, Fournisseur: Connectez-vous pour afficher
Antigène
  • P62DOK
  • Dok-1
  • AW557123
  • p62DOK
  • dok1
  • zgc:76914
  • docking protein 1
  • docking protein 1b
  • DOK1
  • Dok1
  • dok1b
Épitope
pTyr398
47
44
15
14
10
10
8
6
4
4
4
3
3
3
2
2
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
225
142
139
6
6
4
4
4
Hôte
Lapin
223
4
Conjugué
Cet anticorp DOK1 est non-conjugé
8
8
8
3
3
3
3
3
3
3
3
3
3
3
2
2
2
Application
Immunohistochemistry (IHC)
183
100
66
39
33
19
13
7
4
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).
Specificité P62Dok (phospho-Tyr398) antibody detects endogenous levels of p62Dok only when phosphorylated at tyrosine 398.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others DOK1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation p62Dok (DOK1 Antibody Extrait)
Indications d'application WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Simoncic, Bourdeau, Lee-Loy, Rohrschneider, Tremblay, Stanley, McGlade: "T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4149-60, 2006 (PubMed).

Yopp, Ochando, Mao, Ledgerwood, Ding, Bromberg: "Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 5, pp. 2913-24, 2005 (PubMed).

Wick, Dong, Hu, Langlais, Liu: "Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt." dans: The Journal of biological chemistry, Vol. 276, Issue 46, pp. 42843-50, 2001 (PubMed).

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