RPS6KA3 anticorps (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3) (pThr348)

Details for Product anti-RPS6KA3 Antibody No. ABIN966786, Fournisseur: Connectez-vous pour afficher
Antigène
  • CLS
  • HU-3
  • ISPK-1
  • MAPKAPK1B
  • MRX19
  • RSK
  • RSK2
  • S6K-alpha3
  • p90-RSK2
  • pp90RSK2
  • MPK-9
  • Rsk2
  • RGD1563860
  • ribosomal protein S6 kinase A3
  • ribosomal protein S6 kinase polypeptide 3
  • RPS6KA3
  • Rps6ka3
Épitope
pThr348
19
19
19
17
15
15
14
11
10
8
8
7
6
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
253
162
122
9
8
7
6
4
3
3
2
2
2
1
1
1
1
1
1
1
Hôte
Lapin
237
29
Conjugué
Cet anticorp RPS6KA3 est non-conjugé
10
10
10
6
6
6
5
5
5
5
5
5
5
5
5
4
4
Application
Immunohistochemistry (IHC)
170
70
68
67
33
32
23
17
9
6
4
3
3
2
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from mouse p90RSK around the phosphorylation site of threonine 348 (S-R-TP-P-R).
Specificité P90RSK (phospho-Thr348) antibody detects endogenous levels of p90RSK only when phosphorylated at threonine 348.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others RPS6KA3 products on genomics-online (e.g. as negative or positive controls)
Autre désignation p90RSK (RPS6KA3 Antibody Extrait)
Pathways Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Indications d'application WB: 1:500~1:1000
IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Wingate, Campbell, Peggie, Arthur: "Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation." dans: The Biochemical journal, Vol. 393, Issue Pt 3, pp. 715-24, 2006 (PubMed).

Produit citée dans: Itoh, Ding, Bains, Wang, Takeishi, Jalili, King, Walsh, Yan, Abe: "Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation." dans: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 24135-42, 2005 (PubMed).

Silverman, Frödin, Gammeltoft, Maller: "Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells." dans: Molecular and cellular biology, Vol. 24, Issue 24, pp. 10573-83, 2004 (PubMed).

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