pan Keratin (panKRT) anticorps

Détails pour le produit réf. ABIN966801, Fournisseur: Connectez-vous pour afficher
Antigène
  • xk70a
  • keratin
  • keratin S homeolog
  • LOC431321
  • krt.S
Reactivité
Humain
303
197
167
111
74
66
56
54
53
52
49
49
25
11
2
2
2
1
1
Hôte
Souris
218
93
4
Clonalité (Clone)
Monoclonal ()
Conjugué
Inconjugué
10
10
9
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
3
3
3
3
3
3
3
3
3
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
180
175
168
97
84
65
43
30
25
21
15
5
2
1
1
Options
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N° du produit (Fournisseur)
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Immunogène Keratin fraction isolated from cultured cell line A-431, epidermoid carcinoma of vulva.
Clone B311-1
Isotype IgG1
Specificité This antibody recognizes keratin polypeptides with molecular weights of 59, 58, 56, 52.5, 56.5, 54 and 45 kD, which correspond to cytokeratins 4,5,6,8,10,13 and 18.
Purification Prediluted.
Antigène
Autre désignation Pan Cytokeratin
Indications d'application This antibody is prediluted for Immunohistochemistry use.
Staining Procedure: The prediluted antibody can be used on frozen cryostat sections as well as formalin-fixed paraffinembedded tissue sections. For paraffin-embedded tissue sections, we recommend an incubation time and temperature of 30 minutes at 37°C for this antibody, when used in conjunction with immunoperoxidase staining kit. Prolonged fixation in buffered formalin can destroy the epitope.
Commentaires

Recommended Positive Control: Skin, Colonic Carcinoma.

Restrictions For Research Use only
Format Liquid
Concentration 0.005-0.006 mg/ml.
Stock 4 °C
Background publications Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." dans: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991 (PubMed).

Moll, Franke, Schiller, Geiger, Krepler: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." dans: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).

Produit citée dans: Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." dans: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, 1989 (PubMed).

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