Progesterone Receptor anticorps (PGR) (AA 731-909)

Details for Product anti-PGR Antibody No. ABIN966828, Fournisseur: Connectez-vous pour afficher
Antigène
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Épitope
AA 731-909
53
45
41
25
23
21
19
17
17
15
15
15
11
10
9
9
8
7
7
7
6
6
5
5
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
611
104
97
26
11
11
9
6
6
5
4
4
2
1
1
1
1
1
1
1
Hôte
Souris
329
292
3
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp Progesterone Receptor est non-conjugé
20
17
16
12
12
12
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
ELISA, Western Blotting (WB)
463
203
168
132
101
67
51
28
27
27
19
9
3
3
2
2
1
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène Purified recombinant fragment of PGR (aa731-909) expressed in E. Coli.
Clone 2C11F11
Isotype IgG2b
Purification Ascitic fluid
Plasmids, Primers & others Plasmids, Primers & others Progesterone Receptor products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PGR (PGR Antibody Extrait)
Sujet PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Synonyms: PR, NR3C3, PGR
ID gène 5241
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Indications d'application Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Produit citée dans: Polo, José Galindo, Martínez, Alvarez, Arévalo, Asensi, Cánoves, Cáncer, Collazos, Estrada, Gómez-Candela, Johnston, Locutura, López-Aldeguer, Lozano, Miralles, Muñoz-Sanz, Ortega, Pascua, Pedrol, Pulido, San Martín, Sanz, Viciana, Chamorro,: "[Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in patients with HIV infection]." dans: Enfermedades infecciosas y microbiología clínica, Vol. 24, Issue 2, pp. 96-117, 2006 (PubMed).

Background publications Tung, Abdel-Hafiz, Shen, Harvell, Nitao, Richer, Sartorius, Takimoto, Horwitz: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." dans: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, 2006 (PubMed).

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