PKC beta anticorps (Protein Kinase C, beta) (pThr642)

Details for Product anti-PRKCB Antibody No. ABIN966835, Fournisseur: Connectez-vous pour afficher
Antigène
  • PKC-beta
  • PKCB
  • PRKCB1
  • PRKCB2
  • A130082F03Rik
  • PKC-Beta
  • Pkcb
  • Prkcb1
  • Prkcb2
  • PKC-B
  • Prkcb
  • prkcb1
  • zgc:63591
  • PKC
  • PRKCB_tv2
  • protein kinase C beta
  • protein kinase C, beta
  • protein kinase C, beta b
  • PRKCB
  • Prkcb
  • prkcbb
Épitope
pThr642
28
17
17
13
13
10
9
8
8
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
151
105
105
21
20
15
10
6
5
4
2
2
2
2
2
2
1
1
Hôte
Lapin
163
16
7
6
Conjugué
Cet anticorp PKC beta est non-conjugé
14
10
5
5
5
5
2
2
2
Application
Immunohistochemistry (IHC)
172
89
80
24
22
11
8
7
6
5
4
3
3
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human PKC around the phosphorylation site of threonine 642 (E-L-TP-P-T).
Specificité PKC (phospho-Thr642) antibody detects endogenous levels of PKC only when phosphorylated at threonine 642.
Autre désignation PKCbeta (PRKCB Antibody Extrait)
Pathways Signalisation WNT, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded protein response
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Zhang, Liao, Dufau et al.: "Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of ..." dans: Molecular and cellular biology, Vol. 26, Issue 18, pp. 6748-61, 2006 (PubMed).

Castoria, Migliaccio, Di Domenico, Lombardi, de Falco, Varricchio, Bilancio, Barone, Auricchio: "Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells." dans: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7643-53, 2004 (PubMed).

Marcil, Harbour, Houle, Naccache, Bourgoin: "Monosodium urate-crystal-stimulated phospholipase D in human neutrophils." dans: The Biochemical journal, Vol. 337 ( Pt 2), pp. 185-92, 1999 (PubMed).

Bornancin, Parker: "Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha." dans: Current biology : CB, Vol. 6, Issue 9, pp. 1114-23, 1997 (PubMed).

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