PKC theta anticorps (Protein Kinase C, theta) (pSer695)

Details for Product anti-PRKCQ Antibody No. ABIN966840, Fournisseur: Connectez-vous pour afficher
Antigène
  • PRKCT
  • nPKC-theta
  • A130035A12Rik
  • AW494342
  • PKC-0
  • PKC-theta
  • PKCtheta
  • Pkcq
  • protein kinase C theta
  • protein kinase C eta
  • protein kinase C, theta
  • PRKCQ
  • PRKCH
  • Prkcq
Épitope
pSer695
47
43
32
18
10
9
4
4
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
229
138
132
12
10
10
7
4
3
2
1
1
Hôte
Lapin
223
22
3
1
Conjugué
Cet anticorp PKC theta est non-conjugé
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
2
2
2
2
Application
Immunohistochemistry (IHC)
171
126
72
49
40
38
15
7
5
3
3
2
2
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human PKC around the phosphorylation site of serine 695 (N-F-SP-F-M).
Specificité PKC (phospho-Ser695) antibody detects endogenous levels of PKC only when phosphorylated at serine 695.
Autre désignation PKCtheta (PRKCQ Antibody Extrait)
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Kim, Sekiya, Poulin, Bae, Rhee: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." dans: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, 2004 (PubMed).

Humphries, Dangelmaier, Sommer, Kipp, Kato, Griffith, Bakman, Turk, Daniel, Rawlings: "Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker." dans: The Journal of biological chemistry, Vol. 279, Issue 36, pp. 37651-61, 2004 (PubMed).

Suzuki-Inoue, Wilde, Andrews, Auger, Siraganian, Sekiya, Rhee, Watson: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." dans: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, 2004 (PubMed).

Rodriguez, Matsuda, Storey, Katan: "Requirements for distinct steps of phospholipase Cgamma2 regulation, membrane-raft-dependent targeting and subsequent enzyme activation in B-cell signalling." dans: The Biochemical journal, Vol. 374, Issue Pt 1, pp. 269-80, 2003 (PubMed).

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