PKD-PKCmu (pSer910) anticorps

Détails pour le produit réf. ABIN966846, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
pSer910
3
2
1
1
Reactivité
Humain, Souris, Rat (Rattus)
9
9
5
Hôte
Lapin
9
Application
Immunohistochemistry (IHC)
6
3
1
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human PKD/PKCµ around the phosphorylation site of serine 910 (R-V-SP-I-L).
Specificité PKD/PKCµ (phospho-Ser910) antibody detects endogenous levels of PKD/PKCµ only when phosphorylated at serine 910.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Autre désignation PKD/PKCmy
Indications d'application WB: 1:500~1:1000
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Background publications Brändlin, Hübner, Eiseler, Martinez-Moya, Horschinek, Hausser, Link, Rupp, Storz, Pfizenmaier, Johannes: "Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways." dans: The Journal of biological chemistry, Vol. 277, Issue 8, pp. 6490-6, 2002 (PubMed).

Matthews, Rozengurt, Cantrell: "Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu." dans: The Journal of biological chemistry, Vol. 274, Issue 37, pp. 26543-9, 1999 (PubMed).

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