EIF2AK2 anticorps

N° du produit ABIN966853

Détail du produit anti-EIF2AK2 anticorps

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Immunohistochemistry (IHC)

Specificité: PKR (Ab-446) antibody detects endogenous levels of total PKR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human PKR around the phosphorylation site of threonine 446 (K-R-TP-R-S).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-EIF2AK2 (ABIN966853)

Guerra, López-Fernández, García, Zaballos, Esteban et al.: "Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN ..." dans: The Journal of biological chemistry, Vol. 281, Issue 27, pp. 18734-45, (2006) (PubMed).

Ryman, Meier, Nangle, Ragsdale, Korneeva, Rhoads, MacDonald, Klimstra: "Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells." dans: Journal of virology, Vol. 79, Issue 3, pp. 1487-99, (2005) (PubMed).

Pataer, Vorburger, Barber, Chada, Mhashilkar, Zou-Yang, Stewart, Balachandran, Roth, Hunt, Swisher: "Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR)." dans: Cancer research, Vol. 62, Issue 8, pp. 2239-43, (2002) (PubMed).

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: PKR (EIF2AK2 Produits)

Synonymes: anticorps PKR, anticorps pkr, anticorps EIF2AK2, anticorps DKFZp469K1934, anticorps EIF2AK1, anticorps PRKR, anticorps 2310047A08Rik, anticorps 4732414G15Rik, anticorps AI467567, anticorps AI747578, anticorps Pkr, anticorps Prkr, anticorps Tik, anticorps eukaryotic translation initiation factor 2 alpha kinase 2, anticorps eukaryotic translation initiation factor 2-alpha kinase 2, anticorps EIF2AK2, anticorps eif2ak2, anticorps Eif2ak2

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C