PTK2B anticorps (PTK2B Protein tyrosine Kinase 2 beta) (pTyr402)

Details for Product anti-PTK2B Antibody No. ABIN966926, Fournisseur: Connectez-vous pour afficher
Antigène
  • CADTK
  • CAKB
  • FADK2
  • FAK2
  • PKB
  • PTK
  • PYK2
  • RAFTK
  • CAKbeta
  • E430023O05Rik
  • Raftk
  • Pyk2
  • fak1b
  • ptk2.2
  • ptk2b
  • si:ch1073-355e8.1
  • protein tyrosine kinase 2 beta
  • PTK2 protein tyrosine kinase 2 beta
  • protein tyrosine kinase 2aa
  • PTK2B
  • Ptk2b
  • ptk2aa
Épitope
pTyr402
55
22
17
15
15
12
11
10
10
9
8
7
7
7
6
5
5
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
287
192
165
12
11
9
8
7
6
5
2
1
1
1
Hôte
Lapin
251
40
3
Conjugué
Cet anticorp PTK2B est non-conjugé
7
7
6
4
3
3
3
3
3
3
3
3
3
3
3
2
2
Application
Immunohistochemistry (IHC)
235
143
128
71
39
29
19
6
4
3
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).
Specificité Pyk2 (phospho-Tyr402) antibody detects endogenous levels of Pyk2 only when phosphorylated at tyrosine 402.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Plasmids, Primers & others Plasmids, Primers & others PTK2B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Pyk2 (PTK2B Antibody Extrait)
Pathways EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Krishnan, Sharma-Walia, Streblow, Naranatt, Chandran: "Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells." dans: Journal of virology, Vol. 80, Issue 3, pp. 1167-80, 2006 (PubMed).

Gluck: "Acid sensing in renal epithelial cells." dans: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1696-9, 2004 (PubMed).

Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: "Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 17, pp. 9784-9, 2001 (PubMed).

Background publications Tian, Litvak, Toledo-Rodriguez, Carmon, Lev: "Nir2, a novel regulator of cell morphogenesis." dans: Molecular and cellular biology, Vol. 22, Issue 8, pp. 2650-62, 2002 (PubMed).

Lu, Jiang, Blume-Jensen, Hunter: "Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase." dans: Molecular and cellular biology, Vol. 21, Issue 12, pp. 4016-31, 2001 (PubMed).

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