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TNFRSF11A anticorps (N-Term)

TNFRSF11A Reactivité: Humain WB Polyclonal unconjugated
N° du produit ABIN966946
  • Antigène Voir toutes TNFRSF11A Anticorps
    TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
    Épitope
    • 16
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-44, N-Term
    Reactivité
    • 66
    • 37
    • 27
    Humain
    Hôte
    Veuillez nous consulter SVP
    Clonalité
    • 56
    • 23
    Polyclonal
    Conjugué
    • 44
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNFRSF11A est non-conjugé
    Application
    • 57
    • 30
    • 26
    • 14
    • 14
    • 13
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Immunogène
    A synthetic peptide corresponding to a sequence at the N-terminal of human RANK (29-44 aa), identical to the related mouse and rat sequence.
    Top Product
    Discover our top product TNFRSF11A Anticorps primaire
  • Indications d'application
    WB: The detection limit for RANK is approximately 2.5ng/lane under non-reducing and reducing conditions.
    Restrictions
    For Research Use only
  • Reconstitution
    0.2ml of distilled water will yield a concentration of 500µg/ml.
    Buffer
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Stock
    -20 °C
  • Theill, Boyle, Penninger: "RANK-L and RANK: T cells, bone loss, and mammalian evolution." dans: Annual review of immunology, Vol. 20, pp. 795-823, (2002) (PubMed).

    Suda, Takahashi, Udagawa, Jimi, Gillespie, Martin: "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families." dans: Endocrine reviews, Vol. 20, Issue 3, pp. 345-57, (1999) (PubMed).

  • Antigène
    TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
    Autre désignation
    RANK (TNFRSF11A Produits)
    Synonymes
    anticorps RANK, anticorps RGD1563614, anticorps TNFRSF11A, anticorps Ly109, anticorps ODFR, anticorps OFE, anticorps Rank, anticorps TRANCE-R, anticorps mRANK, anticorps CD265, anticorps FEO, anticorps LOH18CR1, anticorps OPTB7, anticorps OSTS, anticorps PDB2, anticorps TRANCER, anticorps TNF receptor superfamily member 11A, anticorps TNF receptor superfamily member 11a, anticorps tumor necrosis factor receptor superfamily, member 11a, NFKB activator, anticorps Tnfrsf11a, anticorps TNFRSF11A
    Sujet
    Receptor Activator of Nuclear Factor B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.
    Pathways
    Signalisation NF-kappaB
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