RANK anticorps (CD265) (N-Term)

Details for Product anti-CD265 Antibody No. ABIN966946, Fournisseur: Connectez-vous pour afficher
Antigène
  • Ly109
  • ODFR
  • OFE
  • Rank
  • TRANCE-R
  • mRANK
  • CD265
  • FEO
  • LOH18CR1
  • OPTB7
  • OSTS
  • PDB2
  • RANK
  • TRANCER
  • RGD1563614
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • TNF receptor superfamily member 11a
  • TNF receptor superfamily member 11A
  • Tnfrsf11a
  • TNFRSF11A
Épitope
N-Term, AA 29-44
9
5
4
3
3
2
2
1
1
1
1
1
1
1
Reactivité
Humain
68
38
19
Hôte
61
13
9
Clonalité
Polyclonal
Conjugué
Cet anticorp RANK est non-conjugé
7
5
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
54
27
21
19
17
13
12
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène A synthetic peptide corresponding to a sequence at the N-terminal of human RANK (29-44 aa), identical to the related mouse and rat sequence.
Plasmids, Primers & others Plasmids, Primers & others RANK products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation RANK (CD265 Antibody Extrait)
Sujet Receptor Activator of Nuclear Factor B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling.RANKL (Receptor Activator for Nuclear Factor B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al. (1997) mapped the RANK gene to 18q22.1.
Pathways Signalisation NF-kappaB
Indications d'application WB: The detection limit for RANK is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Agent conservateur Thimerosal (Merthiolate), Sodium azide
Stock -20 °C
Produit citée dans: Theill, Boyle, Penninger: "RANK-L and RANK: T cells, bone loss, and mammalian evolution." dans: Annual review of immunology, Vol. 20, pp. 795-823, 2002 (PubMed).

Suda, Takahashi, Udagawa, Jimi, Gillespie, Martin: "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families." dans: Endocrine reviews, Vol. 20, Issue 3, pp. 345-57, 1999 (PubMed).

Background publications Wong, Josien, Choi: "TRANCE is a TNF family member that regulates dendritic cell and osteoclast function." dans: Journal of leukocyte biology, Vol. 65, Issue 6, pp. 715-24, 1999 (PubMed).

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