V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB) (pSer552) anticorps

Détails pour le produit réf. ABIN966959, Fournisseur: Connectez-vous pour afficher
Antigène
  • shep
  • I-REL
  • IREL
  • REL-B
  • XRelB
  • relb-A
  • GC-rich
  • avian reticuloendotheliosis viral (v-rel) oncogene related B
  • RELB proto-oncogene, NF-kB subunit
  • v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog
  • Relb
  • RELB
  • relb.S
Épitope
pSer552
31
19
13
9
6
6
5
5
5
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
173
133
74
14
14
10
8
7
6
3
1
1
1
Hôte
Lapin
175
8
Conjugué
Inconjugué
6
6
4
3
3
3
3
3
3
3
3
3
3
3
1
Application
Immunohistochemistry (IHC)
136
50
40
28
28
14
9
7
5
2
2
2
1
Options
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Immunogène The antiserum was produced against synthesized phosphopeptide derived from human RelB around the phosphorylation site of serine 552 (L-L-SP-P-G).
Specificité RelB (phospho-Ser552) antibody detects endogenous levels of RelB only when phosphorylated at serine552.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Antigène
Autre désignation RelB (RELB Antibody Extrait)
Pathways Signalisation NF-kappaB, Signalisation RTK
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Pyz, Naidenko, Miyake, Yamamura, Berberich, Cardell, Kronenberg, Herrmann: "The complementarity determining region 2 of BV8S2 (V beta 8.2) contributes to antigen recognition by rat invariant NKT cell TCR." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 12, pp. 7447-55, 2006 (PubMed).

Kaetzel: "The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces." dans: Immunological reviews, Vol. 206, pp. 83-99, 2005 (PubMed).

Marienfeld, Berberich-Siebelt, Berberich, Denk, Serfling, Neumann: "Signal-specific and phosphorylation-dependent RelB degradation: a potential mechanism of NF-kappaB control." dans: Oncogene, Vol. 20, Issue 56, pp. 8142-7, 2002 (PubMed).

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