RUNX1 anticorps (Runt-Related Transcription Factor 1)

Details for Product anti-RUNX1 Antibody No. ABIN966980, Fournisseur: Connectez-vous pour afficher
Antigène
  • RUNX1
  • runx1
  • AI462102
  • AML1
  • Cbfa2
  • Pebp2a2
  • Pebpa2b
  • AML1-EVI-1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • runxa
  • Runx-1
  • XAML
  • Xaml1
  • aml
  • aml-1
  • aml1
  • aml1-evi-1
  • amlcr1
  • cbfa2
  • evi-1
  • pebp2ab
  • Aml1
  • uncharacterized LOC473981
  • runt-related transcription factor
  • runt related transcription factor 1
  • runt-related transcription factor 1
  • runt related transcription factor 1 L homeolog
  • LOC473981
  • runt
  • Runx1
  • RUNX1
  • runx1
  • runx1.L
Reactivité
Humain
284
125
108
20
17
17
16
14
12
9
8
6
2
2
1
1
1
1
Hôte
Souris
199
82
3
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp RUNX1 est non-conjugé
6
6
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
232
138
91
75
54
37
27
22
7
6
4
3
3
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Synthesized peptide of human RUNX1.
Clone 2B5
Isotype IgG1
Purification Ascitic fluid
Autre désignation RUNX1 (RUNX1 Antibody Extrait)
Sujet Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Synonyms: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI1, RUNX1
Poids moléculaire 55kDa
ID gène 861
Indications d'application Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Background publications Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." dans: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, 2008 (PubMed).

Produit citée dans: Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, 2008 (PubMed).

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