SARS-CoV M Protein anticorps

Détails pour le produit réf. ABIN966994, Fournisseur: Connectez-vous pour afficher
Antigène
Reactivité
Humain, Souris
15
6
3
3
1
Hôte
Souris
13
12
Clonalité (Clone)
Monoclonal ()
Application
ELISA, Western Blotting (WB)
19
16
2
2
2
2
1
1
1
Options
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Immunogène Purified recombinant fragment of SARS-m protein expressed in E. Coli.
Clone 2H2C4
Isotype IgG1
Purification Subclonal supernatant.
Autre désignation SARS-M
Sujet SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The complete sequence of the SARS virus release the coronavirus contains 25 open reading frames. SARS-m is a membrane (M) protein which plays a the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope.
Indications d'application Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Stock 4 °C
Produit citée dans: de Haan, Smeets, Vernooij, Vennema, Rottier: "Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein." dans: Journal of virology, Vol. 73, Issue 9, pp. 7441-52, 1999 (PubMed).

Blomhoff, Smedsrød, Eskild, Granum, Berg: "Preparation of isolated liver endothelial cells and Kupffer cells in high yield by means of an enterotoxin." dans: Experimental cell research, Vol. 150, Issue 1, pp. 194-204, 1984 (PubMed).

Background publications Fournel, Morel, Revillard, Lizard, Bonnefoy-Berard: "Inhibition of human T cell response to staphylococcal enterotoxin B by prior ligation of surface CD4 molecules." dans: Cellular immunology, Vol. 150, Issue 1, pp. 194-204, 1993 (PubMed).

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