Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SVMT(Synaptic vesicular amine transporter)
SLC18A2
Reactivité: Humain, Rat, Souris
WB, IHC, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Stock
4 °C
Thiriot, Sievert, Ruoho: "Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond." dans: Biochemistry, Vol. 41, Issue 20, pp. 6346-53, (2002) (PubMed).
Peter, Finn, Klisak, Liu, Kojis, Heinzmann, Roghani, Sparkes, Edwards: "Chromosomal localization of the human vesicular amine transporter genes." dans: Genomics, Vol. 18, Issue 3, pp. 720-3, (1994) (PubMed).
Surratt, Persico, Yang, Edgar, Bird, Hawkins, Griffin, Li, Jabs, Uhl: "A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs." dans: FEBS letters, Vol. 318, Issue 3, pp. 325-30, (1993) (PubMed).
Erickson, Eiden: "Functional identification and molecular cloning of a human brain vesicle monoamine transporter." dans: Journal of neurochemistry, Vol. 61, Issue 6, pp. 2314-7, (1993) (PubMed).
Antigène
SLC18A2
(Solute Carrier Family 18 (Vesicular Monoamine Transporter), Member 2 (SLC18A2))
anticorps 1110037L13Rik, anticorps 9330105E13, anticorps VAT2, anticorps Vmat2, anticorps MNAT, anticorps VMAT-2, anticorps VMAT2, anticorps solute carrier family 18 (vesicular monoamine), member 2, anticorps solute carrier family 18 member A2, anticorps Slc18a2
Sujet
SVMT(Synaptic vesicular amine transporter) is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. SVMT is requisite for vesicular amine storage prior to secretion via exocytosis. SVMT belongs to the major facilitator superfamily and vesicular transporter family.