AGT anticorps
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- Antigène Voir toutes AGT Anticorps
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp AGT est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human AGT expressed in E. coli.
- Clone
- 1B1
- Isotype
- IgG2b
- Top Product
- Discover our top product AGT Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Role of cardiac overexpression of ANG II in the regulation of cardiac function and remodeling postmyocardial infarction." dans: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 3, pp. H1900-7, (2007) (PubMed).
: "Adrenomedullin inhibits angiotensin II-induced contraction in human aortic smooth muscle cells." dans: Regulatory peptides, Vol. 133, Issue 1-3, pp. 155-9, (2005) (PubMed).
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Role of cardiac overexpression of ANG II in the regulation of cardiac function and remodeling postmyocardial infarction." dans: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 3, pp. H1900-7, (2007) (PubMed).
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- Antigène
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Autre désignation
- AGT (AGT Produits)
- Synonymes
- anticorps ANHU, anticorps SERPINA8, anticorps AI265500, anticorps AngI, anticorps AngII, anticorps Aogen, anticorps Serpina8, anticorps ANRT, anticorps Ang, anticorps PAT, anticorps wu:fb62f06, anticorps wu:fj87b02, anticorps zgc:111892, anticorps AGT, anticorps angt, anticorps ANGT, anticorps angiotensinogen, anticorps angiotensinogen (serpin peptidase inhibitor, clade A, member 8), anticorps AGT, anticorps Agt, anticorps agt
- Sujet
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Description: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Aliases: ANHU
- Poids moléculaire
- 53 kDa
- ID gène
- 183
- HGNC
- 183
- Pathways
- Signalistation JAK/STAT, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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